We implement Ariane design with 136 macros on the NanGate45 platform using the proprietary (commercial) tools Cadence Genus (Synthesis) and Cadence Innovus (P&R), and the open-source tools Yosys (Synthesis) and OpenROAD (P&R).
The screenshot of the design using Cadence Flow-1 on Nangate45 enablement is shown below
The screenshot of the design using ORFS on Nangate45 enablement is shown below